Herramientas diagnósticas avanzadas para la ERGE refractaria: Actualización basada en evidencia
DOI:
https://doi.org/10.70881/mcj/v3/n4/99Palabras clave:
ERGE refractaria, pH-impedanciometría multicanal, Manometría esofágica de alta resolución, EndoFlip, Consenso de LyonResumen
La enfermedad por reflujo gastroesofágico (ERGE) es una afección crónica de alta prevalencia cuyo manejo se complica cuando los síntomas persisten pese al tratamiento con inhibidores de la bomba de protones, configurando la ERGE refractaria y evidenciando las limitaciones de los métodos diagnósticos convencionales. El objetivo de esta revisión fue analizar el rendimiento, las indicaciones y las aplicaciones clínicas de las herramientas diagnósticas avanzadas en la ERGE refractaria. Se realizó una revisión bibliográfica cualitativa de artículos originales, revisiones, metaanálisis y guías clínicas publicados entre 2020 y 2025 en bases de datos de alto impacto, seleccionando estudios relevantes sobre métodos diagnósticos avanzados. La evidencia muestra que la ERGE refractaria comprende un espectro heterogéneo de fenotipos clínicos asociados a reflujo ácido, no ácido o débilmente ácido, hipersensibilidad esofágica y trastornos de la motilidad, lo que justifica el uso de técnicas como la pH-impedanciometría multicanal, la manometría esofágica de alta resolución, EndoFLIP y los criterios del Consenso de Lyon 2.0 para una caracterización fisiopatológica más precisa. En conclusión, el diagnóstico de la ERGE refractaria debe basarse en un enfoque multimodal e individualizado, sustentado en evidencia objetiva, que permita optimizar el tratamiento, evitar intervenciones innecesarias y mejorar la calidad de vida de los pacientes
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Derechos de autor 2025 Valeria del Rosario Orozco Jara, Marlon Alexander Chávez Solano, Estefanía Dayana Caisatoa Cabrera, José David Dávalos Castelo, Paola Esthefania Bonilla Ordoñez (Autor/a)
Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial 4.0.
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